A COMPREHENSIVE MULTIPLEX PCR BASED EXOME-SEQUENCING ASSAY FOR RAPID BLOODSPOT CONFIRMATION OF INBORN ERRORS OF METABOLISM

A comprehensive multiplex PCR based exome-sequencing assay for rapid bloodspot confirmation of inborn errors of metabolism

Abstract Background Tandem mass spectrometry (MS MS) and simple fluorometric assays are currently used in newborn screening programs to detect inborn errors of metabolism (IEM).The aim of the study was to evaluate the clinical utility of exome sequencing as a second tier screening method to assist clinical diagnosis of the newborn.Methods A novel P

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Crisis in Ukraine 2014-2016 Reporting in the British Press

This work is devoted to studying the issue of how the events of the political crisis of 2014-2016 in Ukraine were reflected in the UK media.The main features of the British print media are highlighted, the characteristic features of the British newspaper and journalistic discourse are revealed.The study was conducted on the basis of journalistic te

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Double entry bookkeeping vs single entry bookkeeping

Abstract: A financial management eficiently begin, primarily, with an accounting record kept in the best possible conditions, this being conditioned on the adoption of a uniform forms, rational, clear and simple accounting.Throughout history, there have been known two forms of accounting: the simple and double entry.Romanian society after 1990 unde

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